The CF Foundation recently provided an update on the following research trial.
Hypertonic Saline in Preschoolers (SHIP) ages 3 to 5
This is a Phase 2 randomized placebo control trial. It will look the safety and effectiveness of hypertonic saline (7%) twice a day via jet nebulizer in preschool children. Researchers aim to show that hypertonic saline can be used to help improve mucociliary clearance which may help to prevent airway infections and inflammation. This trial is for children with CF ages 3 to 5 years at the time of enrollment. The trial will last up to 12 months with study visits every 3 months. It will require lung function tests, health questionnaires, and respiratory cultures.
- CFF Link: https://tools.cff.org/Display/dsp_ClinicalResearchHTML.cfm?id=391&IDH=9153430
- ClinicalTrials.gov Link: https://clinicaltrials.gov/ct2/show/NCT02378467